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Instrumentation Amplifier Calculator

This Instrumentation Amplifier Calculator estimates the ideal gain, differential input voltage, and output voltage of a classic three-op-amp instrumentation amplifier.

Use it for first-pass bridge sensor signal conditioning, precision measurement front ends, low-level differential signals, and analog design reviews where the ideal gain equation is appropriate.

Engineering tool

Instrumentation Amplifier Calculator

Calculate ideal three-op-amp instrumentation amplifier gain, differential voltage, and output voltage from V+, V−, Rg, and R.

Non-inverting differential input voltage.

Inverting differential input voltage.

External gain-setting resistor between the first-stage amplifier nodes.

Matched internal resistor used by the ideal three-op-amp gain model.

Output voltage (Vout)

1.05 V

Result console

Output voltage (Vout)
1.05V
Instrumentation gain
21V/V
Differential voltage (V+ - V−)
50mV
Positive input (V+)
150mV
Negative input (V−)
100mV
Gain resistor Rg
1
Internal resistor R
10

Result is valid for the ideal three-op-amp instrumentation amplifier model.

Formula reference

Instrumentation Amplifier Formula

The ideal three-op-amp instrumentation amplifier model assumes matched internal resistors, high input impedance, high common-mode rejection, and valid linear output swing.

Gain = 1 + (2R / Rg)Vdiff = V+ − V−Vout = Gain × (V+ − V−)Vout = Gain × Vdiff

Variable definitions

V+
Positive instrumentation amplifier input
V−
Negative instrumentation amplifier input
Rg
External gain-setting resistor
R
Matched internal gain resistor
Gain
Ideal differential gain
Vout
Ideal output voltage

Variable Description

Positive input V+
The non-inverting measurement input of the instrumentation amplifier.
Negative input V−
The inverting measurement input. The calculator subtracts this value from V+.
Gain resistor Rg
The external resistor that programs the differential gain. Smaller Rg values increase gain.
Internal resistor R
The matched resistor value used in the classic three-op-amp gain equation.
Differential voltage
The measured input difference, calculated as V+ minus V−.
Output voltage
The ideal output voltage before checking real supply rail, output swing, and common-mode limits.

Worked Examples

Example 1: Bridge Sensor Signal

V+
0.15 V
V−
0.10 V
R
10 kΩ
Rg
1 kΩ

Gain = 1 + (2R / Rg); Vout = Gain × (V+ − V−)

Gain = 1 + (2 × 10 kΩ / 1 kΩ) = 21; Vdiff = 0.15 V − 0.10 V = 0.05 V

Vout = 21 × 0.05 V = 1.05 V

A 50 mV bridge signal becomes a 1.05 V ideal output when the instrumentation gain is 21.

Example 2: Small Differential Measurement

V+
2.520 V
V−
2.500 V
R
10 kΩ
Rg
500 Ω

Gain = 1 + (2R / Rg); Vout = Gain × Vdiff

Gain = 1 + (2 × 10 kΩ / 500 Ω) = 41; Vdiff = 2.520 V − 2.500 V = 0.020 V

Vout = 41 × 0.020 V = 0.82 V

A 20 mV differential signal is amplified to 0.82 V in the ideal model.

Instrumentation amplifier basics

The classic topology uses two input buffer amplifiers followed by a differential amplifier stage.

High input impedance

Instrumentation amplifiers are useful with sensors because the inputs load the signal source much less than a simple resistor difference amplifier.

High CMRR

High common-mode rejection helps recover small differential signals even when both inputs sit on a large shared common-mode voltage.

Gain programming

Many instrumentation amplifier circuits set gain with a single external Rg, but real ICs may use manufacturer-specific equations.

Precision measurement

Offset voltage, drift, noise, resistor tolerance, and ADC range become important when amplifying millivolt-level signals.

Bridge sensor applications

Instrumentation amplifiers are common front ends for strain gauges, pressure sensors, load cells, and other bridge-based sensors.

Common Mistakes

Confusing instrumentation and differential amplifiers

A simple differential amplifier does not provide the same high input impedance or CMRR as a classic instrumentation amplifier.

Setting Rg incorrectly

Rg has a strong effect on gain. A value that is too small can create excessive gain and unusable bandwidth.

Ignoring output saturation

The ideal output voltage still must fit within the real amplifier output swing and supply rails.

Ignoring input common-mode range

The inputs may be valid differentially but still outside the real amplifier common-mode operating range.

Assuming all INAs use the same formula

Integrated instrumentation amplifiers often use device-specific gain resistor equations and internal resistor values.

Support reference

FAQ

What is an instrumentation amplifier?

An instrumentation amplifier is a precision differential amplifier with high input impedance and strong common-mode rejection. It is commonly used for sensors, bridge circuits, and low-level measurement signals.

How is instrumentation amplifier gain set?

In the classic three-op-amp model used here, gain is set by the external gain resistor Rg and matched internal resistor R using Gain = 1 + 2R/Rg.

Why is CMRR important?

CMRR describes how well the amplifier rejects voltage that is common to both inputs. High CMRR is important when measuring small differential signals in the presence of large common-mode voltage.

What is the purpose of Rg?

Rg programs the first-stage gain. A smaller Rg produces higher gain, while a larger Rg produces gain closer to one.

Can this calculator model AD620 or INA128?

It can provide a first-pass ideal estimate, but real instrumentation amplifier ICs use device-specific gain equations, resistor values, input range limits, output swing limits, and bandwidth constraints.

Why is my calculated output unrealistic?

The calculated output may exceed the real amplifier supply rails or output swing. Real circuits must also check common-mode input range, load current, offset, noise, and gain bandwidth.

Is an instrumentation amplifier the same as a differential amplifier?

No. Both amplify a voltage difference, but a three-op-amp instrumentation amplifier usually provides much higher input impedance and better common-mode rejection than a simple four-resistor difference amplifier.

Related Engineering Guides

Dedicated op-amp guides are planned for this topic cluster. These guide topics are reserved for future publication and are shown without links until the pages exist.

Planned Engineering Guide

Instrumentation Amplifier Basics

Planned guide covering three-op-amp instrumentation amplifier structure, input buffering, and differential output behavior.

Planned Engineering Guide

Understanding CMRR

Planned guide explaining common-mode rejection ratio, resistor matching, common-mode voltage, and measurement accuracy.

Planned Engineering Guide

Bridge Sensor Signal Conditioning

Planned guide covering strain gauges, bridge sensors, excitation, offset, and instrumentation amplifier front ends.

Planned Engineering Guide

Precision Analog Measurement

Planned guide covering offset, drift, noise, filtering, grounding, and ADC interface considerations.

Engineering Disclaimer

This calculator uses an ideal three-op-amp instrumentation amplifier equation for estimation and education. Real designs must verify supply rails, output swing, input common-mode range, gain bandwidth, offset, drift, noise, resistor tolerance, load current, stability, and device-specific datasheet limits before hardware release.